Kurisu is a neuroscience researcher at an American university, and can speak and read English well. Having had her research published in the academic journal Science at the young age of 18, Makise is extremely talented. She skipped a grade in the American school system. She does not get along with her father and has not spoken to him in many years. Okabe often just calls her assistant or one of a number of nicknames he comes up with, such as "Christina", "the Zombie", and "Celeb Sev", none of which she likes. She is considered a tsundere character; she dislikes this characterization as well, strongly objecting whenever Daru mentions it.